[Reversion of antibiotic-sensitivity of lactic acid bacteria in grafted cultures of lymphoblastoid human cells].

The reversion of the antibiotic sensitivity of lactic acid bacteria: Streptococcus salivarius subsp. thermophilus, Enterococcus faecium, Lactobacillus plantarum have been studied. The phenomenon of the reversion has been fists studied in lactic acid bacteria of different taxonomic groups at their interactions with lymphoblastoid human cells.

[Study of vaginal and intestinal microflora of women in the prenatal period and its correction in dysbacteriosis].

A comparative research of the structure of vaginal and intestinal microflora in norm and at kidney pathologies in women in the prenatal period was carried out. At physiologically normal course of pregnancy microbiocenosis of vagina and intestine does not contain pathogenic and conditional-pathogenic microorganisms. Lactic acid bacteria are fixed within the limits of 10(5)-10(8) CFU/1 ml in the vagina secretion and 10(7)-10(8) CFU/1 g in the intestine content.

[Assessment of probiotics according to the international organizations (FAO/WHO)].

The guidelines of international organizations (FAO/WHO) are presented in the paper for the purpose of estimation of probiotic properties of the strains of microorganisms as well as functional food products in respect of their influence on health. Modern scientific researches served as the basis for minimum requirements necessary for the competence of probiotic status. The chart of the experiment sequence is presented that has to be used for probiotics estimation: bacteria systemizing with the use of phenotype and genetic techniques, description of functional properties of the probiotic and estimation of its safety.

[Interferon induction by lacticacid bacteria in vitro and in vivo experiments].

Interferonogenic acitivity of lacticacid bacteria was studied in experiments in vitro and in vivo. It have been shown, that interferon induction depends both on strain species and on culture medium used for lactobacteria harvesting. Streptococcus thermophilus induces interferon more actively in leucocytes (in vitro)--1280 AU/ml on the bines broth medium, and less actively--320 AU/ml on fermented corn medium.