Publications by authors named "T M Gerald"
Introduction: Utilization of neoadjuvant systemic therapy (NAT) prior to radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) is inconsistent, and optimal patient selection for NAT is unclear. The purpose of this study was to evaluate the clinical benefit of NAT in high grade UTUC undergoing RNU.
Materials And Methods: The UTUC Collaborative Network (UCAN) identified patients who underwent RNU for high grade UTUC between 2000 and 2022.
Article Synopsis
- Researchers created AI-based histologic assays to predict the likelihood of recurrence and progression in patients with high-risk non-muscle invasive bladder cancer after treatment with intravesical BCG.
- They analyzed whole-slide images from bladder tumor resections and clinical data from multiple centers, successfully categorizing cases into high or low risk for various outcomes.
- The validation cohort showed that high-risk patients had significantly worse survival outcomes, indicating that these AI assays provide crucial predictive information beyond traditional clinical factors.
Unlabelled: In this study we evaluated outcomes of patients with metastatic renal cell carcinoma who received immunotherapy before surgery. We found that receiving immunotherapy combinations before surgery can offer patients benefits in reducing tumor size and improving disease control.
Background: Immunotherapy (IO) has improved outcomes for patients with metastatic renal cell carcinoma (mRCC).
Background: Penile squamous cell carcinoma (PSCC) is a rare malignancy that may be cured in cases of local disease by resection of the primary tumor. Risk factors and patterns of local recurrence (LR) have not been well described in cases requiring partial or radical penectomy. In this study, we evaluated risk factors for LR and the impact of frozen and final margin assessment.
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