Publications by authors named "T M Fulcher"
Article Synopsis
- Angiosperms are vital for ecosystems and human life, making it important to understand their evolutionary history to grasp their ecological dominance.
- The study builds an extensive tree of life for about 8,000 angiosperm genera using 353 nuclear genes, significantly increasing the sampling size and refining earlier classifications.
- The findings reveal a complex evolutionary history marked by high gene tree conflict and rapid diversification, particularly during the early angiosperm evolution, with shifts in diversification rates linked to global temperature changes.
Significance: We evaluate the relationship between tear film osmolarity measurements and quality of vision in patients presenting for routine eye clinic appointments. We found that the hyperosmolar group (>316 mOsm/L) had a worse quality-of-vision score than the normal osmolarity group, with glare being the most problematic symptom.
Purpose: Quality of vision is a perception and measure of real-world vision, which is not measured routinely in a clinical setting.
Purpose: To report the margin control process and rate of recurrence of periocular basal cell carcinomas (BCCs) managed by en-face, frozen section margin controlled (FSC), excision by a single surgeon with a 3-year follow-up.
Methods: A retrospective analysis of all histopathologically proven cases of periocular BCC who underwent surgical excision with intra-operative, en-face, FSC, excision by a single surgeon from 2015 to 2019 was performed. Patients with less than 3-year follow-up were offered a virtual appointment to determine possible recurrence.
In this report, we present a case of a patient with a 30-year history of orbital asymmetry who presented with metastatic human epidermal growth factor receptor 2 () positive lacrimal/salivary gland ductal adenocarcinoma. The patient was treated with chemoradiotherapy and trastuzumab. Tumours of lacrimal gland origin are rare, and unfortunately can frequently present in late stage.
View Article and Find Full Text PDFAims: To review the distribution of histopathological diagnoses and visual outcome of orbital biopsy in an Irish tertiary referral centre over a 10-year period.
Methods: This was a retrospective, clinical-histopathological case series. Clinical records of all patients who underwent orbital biopsy between January 2008 and January 2018 in the Mater Misericordiae University Hospital were reviewed using data collected from theatre logbooks and hospital-based medical records.