Diagnostic performance of SPECT/CT for identification of aseptic loosening after total knee and hip arthroplasty: a systematic review and meta-analysis.

Despite an increasing number of studies examining the effect of Single-Photon Emission Computed Tomography/ Computed Tomography (SPECT/CT) on improvement of diagnosis of aseptic loosening, there is still a great deal of uncertainty regarding its applicability in diagnostic algorithm. Therefore, in this meta-analysis, we aimed to investigate the diagnostic performance of SPECT/CT for identification of aseptic loosening in patients with persistent pain following the total knee arthroplasty (TKA) and total hip arthroplasty (THA). Electronic databases including Medline, Scopus, Web of Science, Cochrane library, and Embase were systematically searched for identifying relevant published studies from their inception to April 2023.

When Stroke Disguises as Dementia: A Case of Missed Cerebral Venous Thrombosis.

Cerebrovascular thrombosis is among the most critical medical conditions, making early diagnosis and management crucial. Although some symptoms of cerebrovascular thrombosis are typical and lead to early diagnosis, they can sometimes present with rare and unusual symptoms, complicating the diagnostic process. Given the morbidity and mortality associated with these events, it is important to be aware of unexpected symptoms to diagnose and manage these patients more accurately and rapidly.

Alteration of miR-21, miR-433 and miR-590 tissue expression related to the TGF-β signaling pathway in ulcerative colitis patients.

Ulcerative colitis (UC) is an inflammatory disease, and studies have suggested a role for TGF-β signalling pathway in the pathogenesis of UC. In the present study, we evaluated expression of TGF-β signalling genes and their regulatory microRNAs in patients with UC and control subjects. The expression of TGF-β1, SMAD2, SMAD3, miR-21, miR-101, miR-433, and miR-590 were evaluated using real-time PCR in biopsy samples of the patients and controls.