Publications by authors named "T M De Feo"
Total hepatectomy and liver transplantation has emerged as a game-changing strategy in the treatment of several liver-confined primary or metastatic tumors, opening the new era of transplant oncology. However, the expansion of indications is going to worsen the chronic scarcity of organs, and new strategies are needed to enlarge the donor pool. A possible source of organs could be developing split liver transplantation (SLT) programs.
View Article and Find Full Text PDFAssessing the reliability of rapid frozen tissue sections from pre-transplant kidney biopsies in DCD donors and correlations with clinico-pathological data: a pilot study.
Updates Surg
December 2024
Article Synopsis
- Donations after circulatory death face challenges like obtaining family consent, requiring specialized personnel, and time-sensitive organ evaluations, which can harm the organ.
- The current method for evaluating organs involves a lengthy process of preparing formalin-fixed paraffin-embedded samples, but extemporaneous frozen biopsies are considered a less reliable alternative.
- This study examines the effectiveness of frozen biopsy samples in detecting organ issues compared to the standard FFPE samples and correlates two clinical markers—serum creatinine levels and warm ischemia time—with kidney transplant outcomes.
Background: The challenge of transplant waiting-lists is to provide organs for all candidates while maintaining efficiency and equity.
Aims: We investigated the probability of being transplanted or of waiting-list dropout in Italy.
Methods: Data from 12,749 adult patients waitlisted for primary liver-transplantation from January 2012 to December 2022 were collected from the National Transplant-Registry.