Publications by authors named "T M Buzug"
Mandibular advancement devices are an effective treatment option for obstructive sleep apnea. While their efficacy depends on the degree of mandibular protrusion, other contributing factors influencing the optimal outcome are not fully understood. This magnetic resonance imaging-based pilot study aimed at investigating whether there are promising planimetric parameters that may be related to the optimal therapeutic position.
View Article and Find Full Text PDFArticle Synopsis
- Mandibular advancement devices (MAD) effectively treat mild to moderate obstructive sleep apnea (OSA) and are particularly beneficial for patients with high night-to-night variability (NNV).
- A study revealed that a 60% protrusion distance of MAD significantly reduced apnea-hypopnea index (AHI) and improved sleepiness levels compared to 80% protrusion, though the latter showed no significant change.
- The results suggest that while higher NNV is linked to severe OSA, it does not automatically disqualify patients from MAD treatment, indicating a need for future research to enhance the relationship between objective OSA measures and patient-reported outcomes (PRO).
Purpose: Magnetic particle imaging (MPI) is an emerging medical imaging modality that is on the verge of clinical use. In recent years, cardiovascular applications have shown huge potential like, e.g.
View Article and Find Full Text PDFArticle Synopsis
- Combining magnetic particle imaging (MPI) and magnetic fluid hyperthermia (MFH) enables targeted heating in the body and improved monitoring of treatment without surgery.
- The paper presents a new design for MFH systems that can be integrated into existing MPI scanners, overcoming challenges like magnetic interference that could damage the imaging equipment.
- The developed integrable platforms ensure safe magnetic and electrical operations, allowing for precise heating techniques and enhancing the potential for future medical trials involving advanced cancer treatments.
Theranostic platforms, combining diagnostic and therapeutic approaches within one system, have garnered interest in augmenting invasive surgical, chemical, and ionizing interventions. Magnetic particle imaging (MPI) offers a quite recent alternative to established radiation-based diagnostic modalities with its versatile tracer material (superparamagnetic iron oxide nanoparticles, SPION). It also offers a bimodal theranostic framework that can combine tomographic imaging with therapeutic techniques using the very same SPION.
View Article and Find Full Text PDF