Publications by authors named "T M Bowles"

Background: Rural general surgeons require a diverse skillset to manage the varied work required in regional settings. Access to appropriate surgical services is important but challenging due to a lack of resident rural surgeons and increasing surgical subspecialisation.

Method: This is a retrospective multi-centre study on procedures undertaken within the General Surgery departments of two regional centres in Western Australia; Albany Health Campus (AHC) and Bunbury Regional Hospital (BRH).

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Introduction: Women with hypertensive disorders of pregnancy such as HELLP (hemolysis, elevated liver enzyme, low platelet) Syndrome are affected by acute kidney injury during pregnancy (PR-AKI) at higher rates than women without hypertension. Both hypertensive disorders of pregnancy and Acute Kidney Injury (AKI) outside the context of pregnancy have been associated with an increased risk of developing Chronic Kidney Disease (CKD) and cognitive impairment. In our current study, we set out to determine if PR-AKI led to the development of CKD and impaired cognition in the postpartum period and if HELLP syndrome exacerbates the impairments.

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Article Synopsis
  • Floral traits like flower size and nectar/pollen rewards are crucial for attracting pollinators, but these traits can vary due to environmental factors and soil conditions.
  • Research shows that diverse arbuscular mycorrhizal fungi (AMF) can improve floral displays and rewards, leading to increased bee visitation, as larger flowers attract more bees.
  • However, there's a trade-off, as enhanced flower size from AMF may reduce root colonization, indicating that soil microbial interactions significantly influence both plant traits and pollinator behavior.
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  • Viral infections (VIs) can lead to T-cell exhaustion, potentially hindering the immune system's ability to fight melanoma, which may increase mortality rates in these patients.
  • A study using data from 17,754 melanoma patients found that those with a history of VIs had a statistically significant 33% higher risk of dying from melanoma compared to those without such a history.
  • Further research is needed to understand how different types and durations of VIs impact this association with melanoma-specific mortality.
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Introduction: Gene expression profiling (GEP) of primary cutaneous melanoma aims to offer prognostic and predictive information to guide clinical care. Despite limited evidence of clinical utility, these tests are increasingly incorporated into clinical care.

Methods: A panel of melanoma experts from the Society of Surgical Oncology convened to develop recommendations regarding the use of GEP to guide management of patients with melanoma.

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