A ten-year analysis of changes in the sensitivity of the leading uropathogen to antibacterial agents in children with urinary tract infection in the nephrology department.

Objective: The aim: To study the prevalence of ABR among children with UTI over the past 10 years, with an assessment of the sensitivity of E. Coli to common antibiotics in dynamics.

Patients And Methods: Materials and methods: The study involved 1,044 children with UTI aged from 1 month to 18 years.

Bone tissue lesion in oncological disease (literature review and own research data).

A review of the current literature and our own researches data are presented. Malignant tumors all over the world cause a huge medical social and economic damage, being one of the main causes of people death in all countries. Involving bones in the pathological process occurs in every other patient with cancer.

GOODPASCHER'S SYNDROME - THE CHALLENGES IN A TIMELY DIAGNOSIS AND TREATMENT IN MEDICAL PRACTICE (CLINICAL CASE).

The article presents a clinical case with intravital diagnosis of Goodpascher's syndrome in a 22 years old patient. In this work we analyze clinical, laboratory-instrumental, pathologoanatomic and pathomorphological aspects of the disease, which was accompanied by glomerulonephritis with rapidly progressive renal insufficiency, anemia, arterial hypertension and symptoms of lung injury. Article emphasizes on the necessity of timely diagnosis of Goodpascher's syndrome and following administration of immunosuppressive therapy.

[A complex clinical case of polyarteritis nodosa through the prism of kidneys].

Polyarteritis nodosa is a chronic systemic vasculitis, characterized by the autoimmune, necrotising lesion of the walls of the small- and medium-bore visceral and peripheral arteries, resulting in vessel aneurysms and the secondary degeneration of organs and systems. All types of vessels (arteries, veins, capillaries) can be affected or, alternatively, the process can be limited predominantly to the vessels of one system, the clinical symptoms depending on the bore and location of the affected vessels. Varying degrees of the lesion, varying combinations and sequencing, the compensation abilities of the vessel disorders can blur the clinical picture, even though early pathomorphological changes are quite pronounced.