Activity of Phosphate-Dependent Glutaminase in the Brain of Rats Exposed to Prenatal Hypoxia during Organogenesis.

We studied the effect of hypoxia (days 9-15 of pregnancy) on phosphate-dependent glutaminase activity in the brain of rat offspring aging 18 days and 1, 3, and 6 months. Activity of glutaminase significantly increased in mitochondria from the orbital, visual, and limbic cortex, hypothalamus, and midbrain of 17-day-old offspring. Activity of this enzyme in all brain regions increased at the age of 1 month, but significantly decreased in animals aging 3 and 6 months and prenatally exposed to hypoxia (during organogenesis).

[Study of visual perception under conditions of extreme light exposures].

Neurophysiological processes of transduction and analysis of information concerning brightness of photostimuli and peculiarities of functioning of visual system under exposure to extra-bright light effects or extreme contrasting of visual objects are studied poorly and present significant interest for unraveling actual mechanisms of visual perception under extreme conditions. Conducting analysis of visual system in maximal broad range both in terms of adequate perception and reflection of light stimulus intensity and adaptive mechanisms to extra-strong illumination regimes is as well very important. The to-date obtained data indicate that under the extreme light effects pathology of the peripheral portion of visual analysator can be induced.

[The distribution of aspartate aminotransferase activity in the structures of the visual analyzer in the canine brain during postnatal ontogeny].

Studies have been made on aspartate aminotransferase activity in light and heavy synaptosomes, membrane and synaptic mitochondria from the visual cortex (field 17), bigeminal bodies, and outer geniculate body. It was shown that the enzymic activity significantly decreases in all the subfractions investigated in puppies beginning from 6 months up to 1 year. In earlier postnatal ontogenesis, the activity increased in all the subfractions, the extent of the increase being dependent on the source of the enzyme.

[Complex endoscopic ultrasonographic diagnosis of esophageal diseases].

Complex endoscopic and transesophageal ultrasonic examination makes it possible to identify distinctly the character and localization of the pathological process, its boundaries and its spread to the adjoining organs. Ultrasonic examination is especially effective in new growths of the esophagus.