Fluoroquinolone Resistance in Drug-Resistant Tuberculosis, Kharkiv, Ukraine, 2019-2023.

Rifampin-resistant Mycobacterium tuberculosis was identified by the World Health Organization as a pathogen of public health critical importance. During 2014-2023, an increase in fluoroquinolone resistance in rifampin-resistant M. tuberculosis from Kharkiv, Ukraine, was observed.

THE EFFECT OF MELATONIN ON THE SERUM LEVEL OF INTERLEUKIN 31 IN HERPESVIRUS SKIN DISEASES ON THE BACKGROUND OF HIV.

The immune system of the skin is the first line of defense against various infections, on the other hand, its strategic location as a key barrier between external and internal environment makes the skin an important tool for maintaining homeostasis, so dermatological lesions are often a manifestation of various pathological conditions. Thus, herpesvirus skin diseases, which are the result of reactivation of a latent infection and occur against the background of human immunodeficiency, may be the first manifestation of HIV. Active study of melatonin in recent years in the dermatological field is associated with interest in its biological action, which extends to the skin due to the melatoninergic system, and promising prospects for the development of new treatments.

[CLINICAL AND IMMUNOLOGICAL FEATURES OF HERPESVIRUS DISEASES ON THE BACKGROUND OF HIV].

Herpesvirus infections (HI) are the most common HIV-associated diseases. Due to the development of the HIV pandemic, the incidence of HI against the background of HIV infection is steadily increasing, and the implantation of HAART makes certain changes in the course of diseases of this category. The aim of the study was to compare clinical and immunological data in different forms of HI in HIV-positive patients and in patients with normal immune status.

Morphological features of non-parenchymal liver cells of full-term stillbirths from HIV-mono-infected mothers.

Fifty-one liver tissue biopsies of full-term stillbirths from HIV-mono-infected mothers were investigated. All morphometric indices of non-parenchymal liver cells were calculated using the Avtandilov microscopic morphometric grid, which consisted of 100 equidistant points. It was inserted into the microscope ocular tube with a total × 200 microscope magnification.

THE MORPHOMETRIC PARAMETERS OF THE PARENCHYMAL AND STROMAL LIVER COMPONENTS OF HEALTHY NEWBORNS FROM HEALTHY MOTHERS WITH A PHYSIOLOGICAL COURSE OF PREGNANCY.

Objective: The aim: To determine the morphometric parameters of the parenchymal and stromal liver components of healthy newborns.

Patients And Methods: Material and methods: The morphometric investigation included 45 liver tissue biopsies of healthy newborns. All morphometric parameters of the parenchymal and stromal liver components were calculated using the Avtandilov microscopic morphometric grid.