Global impact of ten-valent and 13-valent pneumococcal conjugate vaccines on invasive pneumococcal disease in all ages (the PSERENADE project): a global surveillance analysis.

Background: Pneumococcal conjugate vaccines (PCVs) that are ten-valent (PCV10) and 13-valent (PCV13) became available in 2010. We evaluated their global impact on invasive pneumococcal disease (IPD) incidence in all ages.

Methods: Serotype-specific IPD cases and population denominators were obtained directly from surveillance sites using PCV10 or PCV13 in their national immunisation programmes and with a primary series uptake of at least 50%.

Estimated number of reported vaccine-preventable disease cases averted following the introduction of routine vaccination programs in Sweden, 1910-2019.

Background: Routine childhood vaccination programs have had enormous positive public health impacts worldwide. However, in some areas, these benefits may be impeded by vaccine hesitancy and undervaccination. We estimated the number of reported cases of measles, pertussis, mumps and poliomyelitis averted in Sweden after the introduction of routine childhood vaccination programs.

Primary diphtheria immunisation of adolescents and adults with low-dose vaccine, a survey of historic evidence from the literature.

The Public Health Agency of Sweden carried out a literature review on diphtheria vaccinations for seronegative people above 6 years of age with an uncertain vaccine history. The aim was to harmonise national Swedish recommendations with the current World Health Organization recommendations. There was no firm conclusion about dosage.

Emergence of the less common cannabinoid Δ -Tetrahydrocannabinol in a doping sample.

Δ -Tetrahydrocannabinol (Δ -THC) as isomer of the well-known Δ -THC has a similar mode of action, and the potency was estimated to be two thirds compared with Δ -THC. Content of Δ -THC in plant material is low, but formulations containing Δ -THC in high concentrations are gaining popularity. Δ -THC is to be regarded as prohibited substance according to the Prohibited List of the World Anti-Doping Agency (WADA).

National Swedish survey showed that child health services and routine immunisation programmes were resilient during the early COVID-19 pandemic.

Aim: Routine immunisation programmes are at risk of disruption due to the COVID-19 pandemic. This study aimed to investigate the resilience of the Swedish national immunisation programme for children up to the age of five years during the early stages of the pandemic.

Methods: This was a cross-sectional, web-based survey of regional child health offices in Sweden between 10 September and 9 October 2020.