Publications by authors named "T Launay"
Transcription factor (TF) binding to DNA is critical to transcription regulation. Although the binding properties of numerous individual TFs are well-documented, a more detailed comprehension of how TFs interact cooperatively with DNA is required. We present COBIND, a novel method based on non-negative matrix factorization (NMF) to identify TF co-binding patterns automatically.
View Article and Find Full Text PDFBed bug infestations have been increasing worldwide since the 2000s. Their consequences for health range from skin reactions to major psychological distress. However, epidemiological data is still lacking.
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- The study investigated the prevalence and bleeding risk associated with drug interactions between apixaban or rivaroxaban and certain CYP3A4 and P-glycoprotein inhibitors in patients with atrial fibrillation (AF).
- Using a cohort from the French healthcare database (2014-2019), 10,392 AF patients on these medications were analyzed, with a focus on hospitalization due to bleeding as the primary outcome.
- The findings revealed a 38.9% prevalence of drug-drug interactions, but no significant association with increased hospitalization for bleeding; factors like age and male gender were related to higher bleeding risk instead.
Exercise Dose Equalization in High-Intensity Interval Training: A Scoping Review.
Int J Environ Res Public Health
April 2022
Based on comparisons to moderate continuous exercise (MICT), high-intensity interval training (HIIT) is becoming a worldwide trend in physical exercise. This raises methodological questions related to equalization of exercise dose when comparing protocols. The present scoping review aims to identify in the literature the evidence for protocol equalization and the soundness of methods used for it.
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