Publications by authors named "T Lankov"

Article Synopsis
  • The incidence of early-onset colorectal cancer (diagnosed in individuals under 50) is on the rise globally, with distinct clinical and molecular characteristics compared to late-onset cases.
  • Factors contributing to this increase may include diet, obesity, antibiotic use, and changes in gut microbiome, with most cases occurring sporadically rather than being genetically inherited.
  • There is a need for tailored preventive and therapeutic approaches for early-onset colorectal cancer, as younger patients often present with more severe disease stages but similar outcomes to older patients after treatment.
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Background: It remains unclear whether extended lymphadenectomy provides oncological advantages in colorectal cancer. This multicentre RCT aimed to address this issue.

Methods: Patients with resectable primary colonic cancer were enrolled in four hospitals registered in the COLD trial, and randomized to D2 or D3 dissection in a 1 : 1 ratio.

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Mechanical bowel preparation used to be a standard procedure for a long time. Nowadays routine use of MBP seems to be debatable thus alternative approaches, e.g.

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