Publications by authors named "T Lalani"
Unlabelled: Neuraminidase (NA)-specific antibodies contribute to immunity against influenza. While studies have demonstrated increased NA inhibiting (NAI) antibody titers after vaccination with egg-derived inactivated influenza vaccines (eIIV), the response to cell culture-derived (c) IIV has not been reported.
Methods: An immunogenicity sub-study was performed within a clinical trial comparing the effectiveness of egg, cell, and recombinant hemagglutinin (HA)-derived influenza vaccines during the 2018-2019 and 2019-2020 influenza seasons.
Article Synopsis
- A study investigated the relationship between COVID-19 vaccination and the risk of developing venous thrombosis or embolism (VTE) after infection, particularly examining the impact of booster shots.
- The research analyzed data from Military Health System beneficiaries who tested positive for COVID-19 between 2020 and 2022, finding that vaccinated individuals had significantly lower odds of developing VTE compared to those unvaccinated.
- Results indicated that the risk of post-COVID-19 VTE was particularly low during the Omicron variant era, and those receiving booster shots had an even greater reduction in VTE risk.
The establishment of the Liver Imaging Reporting and Data System (LI-RADS) in 2011 provided a comprehensive approach to standardized imaging, interpretation, and reporting of liver observations in patients diagnosed with or at risk for hepatocellular carcinoma (HCC). Each set of algorithms provides criteria pertinent to the various components of HCC management including surveillance, diagnosis, staging, and treatment response supported by a detailed lexicon of terms applicable to a wide range of liver imaging scenarios. Before its widespread adoption, the variability in the terminology of diagnostic criteria and definitions of imaging features led to significant challenges in patient management and made it difficult to replicate findings or apply them consistently.
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- * The Liver Imaging Reporting and Data System (LI-RADS) helps standardize liver imaging interpretation by categorizing observations based on their likelihood of cancer or response to treatment.
- * This review outlines common technical challenges in liver imaging, offers solutions to enhance image quality, and discusses new imaging advancements like multi-arterial MR acquisition and compressed sensing to aid radiologists in improving diagnostic accuracy.
Article Synopsis
- The study examined 595 SARS-CoV-2 sequences from Military Health System beneficiaries to assess how vaccination affected viral diversity from December 2020 to April 2022.
- Results indicated that vaccination had limited influence on the diversity of the SARS-CoV-2 spike protein and showed little evidence of a significant sieve effect among major variants.
- The findings suggest that during periods of rapid variant replacement, other factors overshadowed the influence of vaccination on viral diversity, and caution is needed when using sieve analysis methods in non-clinical trial settings.