Publications by authors named "T Labella Caballero"

Hereditary angioedema (HAE) has been recognized for almost 150 years. The newest form of HAE, where C1 inhibitor levels are normal (HAE-nC1INH), was first described in 2000. Over the last two decades, new types of apparent non-mast cell-mediated angioedema with normal quantity and activity of C1INH have been described, in some cases with proven genetic pathogenic variants that co-segregate with angioedema expression within families.

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Article Synopsis
  • Hereditary angioedema (HAE) is a rare condition that causes sudden swelling in the body, which can be dangerous, and needs special care.
  • * There are currently two main ways to manage HAE: having quick access to treatments when episodes happen and preventing attacks with medications.
  • * New oral medications for HAE are being developed and tested, which might make it easier for patients to treat their condition without having to use needles.
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Background: Hereditary angioedema (HAE) is characterized by debilitating attacks of tissue swelling in various locations. While guidelines recommend the importance of early on-demand treatment, recent data indicate that many patients delay or do not treat their attacks.

Objective: This survey aimed to investigate patient behavior and evaluate the key factors that drive on-demand treatment decision-making, as reported by those living with HAE.

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