[Results from the hepatitis A-virus diagnostic of the hygiene-institut in Tübingen].

The age-specific and seasonal distribution of serologically confirmed hepatitis A-cases in the area of Tübingen in southern Germany is reported. During 1978-1980 most of the hepatitis A-cases diagnosed by high anti-HAV-IgM titers occurred from September to December. The age distribution of patients with German names showed two age-related peaks, the first one in young children 5-10 years of age and a second one in young adults between 20-30 years.

[Intravenous immunoglobulin administration for antibody deficiency (author's transl)].

Seven patients received a total of 23 infusions of a polyvalent largely monomeric and intravenously applicable immunoglobulin preparation (Sandoglobulin). Among them are two with congenital antibody deficiency syndrome. One of them, who has agammaglobulinaemia type Bruton, is still receiving 9 g Sandoglobulin every three months.

[Rota virus infection in the newborn and infant -- epidemiological aspects (author's transl)].

In a total of 406 sera an age-dependent pattern of complement fixing antibodies against Rotavirus (Nebraska calf diarrhea virus) was found: 85% of the adults had antibodies, infants in the second half-year of life had the lowest percentage (42%). Thereupon a Rotavirus survey was carried out in a newborn ward by means of electron microscopy, enzyme-linked immunosorbent assay and complement fixation test during three weeks in January/February 1978. A chronically high infection rate was discovered.