We investigated the molecular mechanisms underlying azole resistance in seven isolates that caused candidemia and candiduria in Paraná, Brazil (2016-2022). Biofilm production, antifungal susceptibility testing, multilocus sequence typing, amplification and sequencing of , and quantification of , , and expression levels were performed. Notably, five isolates (71.
View Article and Find Full Text PDFInvasive pneumococcal disease (IPD) is a major cause of morbidity and mortality worldwide, particularly in the pediatric population (children and infants), with high rates of hospitalization and death. This study aimed to create and validate a classifier for serotyping using Fourier-transform infrared (FT-IR) spectroscopy as a rapid alternative to the classical serotyping technique. In this study, a database comprising 76 clinical isolates, including 18 serotypes (predominantly serotypes 19A, 6C, and 3) of from pediatric patients with IPD, was tested at a tertiary pediatric hospital in southern Brazil during 2016-2023.
View Article and Find Full Text PDFThis study aimed to estimate the association of time of energy intake with weight status, diet quality, and sociodemographic characteristics in Brazil. This cross-sectional study used data from a nationally representative survey with 44.744 individuals (≥10 years old).
View Article and Find Full Text PDFBackground And Aims: Polyploidy is an important evolutionary driver for plants and has been linked with higher species richness and increases in diversification rate. These correlations of ploidy with plant radiations could be the result of polyploid lineages exploiting greater niche space and novel niches due to their enhanced adaptability. Ploidy evolution and how it links with diversification of plants across the Australian continent is not well understood.
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