Publications by authors named "T L Skare"
Background: Low vitamin D levels are commonly observed in autoimmune diseases, suggesting a potential role in disease pathogenesis. The presence of anti-vitamin D antibodies may contribute to these deficiencies and influence autoimmune processes.
Objective: To review and analyze studies investigating the occurrence of anti-vitamin D antibodies in autoimmune diseases.
Background: Inflammatory bowel diseases such as Crohn's disease and ulcerative colitis are influenced by environmental and immunological factors and may differ according to the patient's sex.
Objective: The objective was to study the differences in the clinical profile of a Brazilian sample of inflammatory bowel disease patients according to sex.
Methods: Retrospective study with chart review of 158 inflammatory bowel disease patients (43 with Crohn's disease and 115 with ulcerative colitis) from a single university hospital in southern Brazil.
Background: Dyslipidemia is described in several autoimmune conditions. Lipoprotein lipase (LPL) is responsible for triglyceride breakdown. Anti-LPL antibodies have been described.
View Article and Find Full Text PDFArticle Synopsis
- * A total of 29 studies involving 404 patients were analyzed, most focusing on diseases like systemic lupus erythematosus and multiple sclerosis, using a specific dosage and supportive treatments during therapy.
- * The treatment showed improvement in many patients, but some experienced side effects and relapses, indicating that while the approach can be effective, careful monitoring and support are crucial.
Article Synopsis
- Gastrointestinal intolerance is prevalent among rheumatoid arthritis patients using methotrexate, with 55.7% experiencing symptoms, primarily nausea and pain after taking the drug.
- The study identified factors associated with intolerance including afro-descendant background, existing fibromyalgia, and the use of glucocorticoids and Jak inhibitors.
- Logistic regression revealed that using glucocorticoids significantly increased the likelihood of methotrexate intolerance, while adherence to methotrexate was generally moderate.