" Assets Supporting Resilience of Older Adults and Their Communities during the COVID-19 Pandemic.

Despite societal perceptions of older adults as vulnerable, literature on resilience suggests that exposure to adversity and resources gained with life experience contribute to adaptation. One way to explore the nature of resilience is to document assets supporting adaptation. Interviews were conducted with older adults living in Canada at two time points during the COVID-19 pandemic, September 2020-May 2021 (T1) and January-August 2022 (T2).

A child-centred research checklist to improve the design and reporting of paediatric research studies: A descriptive mixed methods study.

Background: No internationally developed child-centred research checklist is currently available to enhance the quality and transparency of the development, reporting and evaluation of research undertaken with children.

Objective: To develop an internationally relevant, expert informed child-centred research checklist.

Design: A descriptive mixed methods study was undertaken in five sequential phases, including a Delphi component.

PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity.

Adipose tissue regulates energy homeostasis and metabolic function, but its adaptability is impaired in obesity. In this study, we investigate the impact of acute PPARγ agonist treatment in obese mice and find significant transcriptional remodeling of cells in the stromal vascular fraction (SVF). Using single-cell RNA sequencing, we profile the SVF of inguinal and epididymal adipose tissue of obese mice following rosiglitazone treatment and find an induction of ribosomal factors in both progenitor and preadipocyte populations, while expression of ribosomal factors is reduced with obesity.

Diffuse Optical Spectroscopy: Technology and Applications: introduction to the feature issue.

Welcome to the 2024 Feature Issue on in Biomedical Optics Express! This feature issue provides an exemplary sample of established and emerging DOS technologies as well as their biomedical applications through 27 contributed research papers and 1 invited review article. DOS researchers are inherently multidisciplinary, advancing topics spanning the basic theory of light-tissue interactions, computational modeling, technique and system development and preclinical and clinical applications. You will find this full range of topics represented in this feature issue.

Occurrence of porcine reproductive and respiratory syndrome clinical outbreaks in Ontario sow herds, 2017 to 2019.

Background: Porcine reproductive and respiratory syndrome (PRRS) is one of the important endemic diseases in swine populations. Monitoring PRRS frequency in commercial herd populations has often been based on laboratory submissions. However, a limitation of this approach is that new clinical outbreaks of PRRS are challenging to identify if epidemiological information is not provided.