Publications by authors named "T L Naneishvili"

High-sensitivity cardiac troponins are considered a gold standard for diagnosing acute myocardial infarction and myocardial injury. However, the occurrence of false positives needs to be kept in mind.  We describe the clinical challenges in diagnosing a 45-year-old woman who repeatedly presented to the emergency department with atypical chest pain and extremely elevated high sensitivity troponin I (HsTnI), despite normal imaging including cardiac MRIs and invasive coronary angiograms, on multiple occasions.

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Article Synopsis
  • Costello syndrome is an autosomal dominant genetic condition linked to variants in a specific gene.
  • Patients commonly experience cardiac issues, such as valvular disease (notably pulmonary stenosis), arrhythmias, and hypertrophic cardiomyopathy.
  • This report highlights the first known case of a dysplastic mitral valve related to Costello syndrome.
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Article Synopsis
  • The study looked at patients with high levels of NT-proBNP to see if it helps in diagnosing heart problems, especially heart failure (HF).
  • Out of 654 patients, many were found to have valve disease, atrial fibrillation (AF), or heart failure, but not everyone with high NT-proBNP had heart failure.
  • The results suggest that while NT-proBNP is good for spotting heart issues in general, it isn't very effective at telling apart heart failure from other heart diseases like valve problems or AF.
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Objectives: To explore the long-term clinical outcomes following intravascular lithotripsy (IVL) in calcified coronary lesions from a real-world population.

Background: IVL is a relatively new but promising modality for treating coronary calcified lesions, but there is a dearth of long-term outcome data from real-world patients.

Methods: This was a multicenter, observational study in which we enrolled all patients treated with IVL from November 2018 to February 2021 from eight centers in Europe and the United Kingdom.

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