[The genetic biochemical markers of arterial hypertension in Adolescents.].

The article deals with studying of enzyme activity of first and second lines of anti-oxidant defense in adolescents with arterial hypertension and establishing role of genetic component in realization of mechanism of development of this pathology. The main group included 20 adolescents aged from 13 to 16 years with diagnosis of arterial hypertension stage I (risk). The control group consisted of 20 healthy adolescents of corresponding age.

Modification of normal activities of angiotensin II and angiotensin IV in rats with experimental hypo- and hyperglycemia.

Changes in blood glucose levels are paralleled by modification of normal activities of angiotensin II and angiotensin IV. Hypo- and hyperglycemia similarly reduced the hypertensive effect of angiotensin II and similarly distorted the initial hypotensive effect of angiotensin IV. Presumably, the adaptation and compensatory processes in the renin-angiotensin system under conditions of shifted homeostatic constants manifest by phenomena of external reintegration and redistribution of functions of its individual peptide components.

[Outpatient screening and its place in better detection of breast tumors].

The authors state their opinion on this problem by analyzing their 5-year use of their programme specially developed for detection of breast disease, mainly cancer, among females visiting specialized rooms of non-mammological profiles (gastroenterology, endocrinology, rheumatology, pulmonology, neurology, cardiology, hematology, nephrology, etc.) in the consulting polyclinics of regional (territorial) hospitals and large city hospital-polyclinic complexes. In this period, mammographic studies were made in 9169 women included into a breast cancer-risk group.

[Clinical x-ray criteria for a differential approach to the surgical treatment of uremic osteodystrophy].

To define the criteria for a differential approach to operative treatment of uremic osteodystrophy arising in hemodialysis 51 patients were examined clinically, biochemically and roentgenologically before and after parathyroidectomy. Basing on the X-ray picture, the patients were divided into 3 groups: patients with fibrous osteodystrophy seen at X-ray examination (group 1); patients with fibrous osteodystrophy, osteomalacia in predominance of secondary hyperthyroidism (group 2); patients with osteodystrophy and osteomalacia in predominance of osteomalacia syndrome (group 3); patients with uremic osteodystrophy diagnosed only biochemically. Parathyroidectomy proved most effective in group 1 patients.