Publications by authors named "T L Lamagni"

Article Synopsis
  • * It outlines the objectives of a study aimed at assessing the effectiveness of various interventions before, during, and after surgery to prevent SSIs and evaluate their impact on patient outcomes.
  • * The study includes a comprehensive search for randomized controlled trials (RCTs) related to SSI prevention in adult cardiac surgery and aims to establish a clearer standard of care for managing these infections.
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is an oral commensal organism belonging to the group (SAG). causes periodontitis as well as invasive, pyogenic infection of the central nervous system, pleural space or liver. Compared with other SAG organisms, has a higher mortality as well as a predilection for intracranial infection, suggesting it is likely to possess virulence factors that mediate specific interactions with the host resulting in bacteria reaching the brain.

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Objectives: In England, group B streptococci (GBS; Streptococcus agalactiae) are considered universally susceptible to penicillin. Reports from Africa, Asia, North America and a few European countries have described GBS isolates with penicillin MICs above the epidemiological cut-off (0.125 mg/L).

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Background: Group B (GBS) significantly contributes to neonatal sepsis and meningitis, with varying disease rates reported globally and limited population-based data. We estimated infant GBS disease burden in Ontario, Canada and assessed the association of maternal GBS screening (35-37 weeks' gestation) and intrapartum antibiotic prophylaxis (IAP) provision with infant disease rates.

Methods: Our population-based cohort study included pregnant individuals and their offspring from April 2012 to March 2018, utilising the provincial birth registry linked to health administrative data.

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Article Synopsis
  • There has been an unusual rise in emergency department visits for pneumonia among children aged 5-14 in England since November 2023.
  • The peak of these visits was noted in March 2024, but high attendance levels continued into early summer 2024.
  • Analysis reveals that this increase was not linked to seasonal respiratory infections, suggesting other factors may be at play.
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