Publications by authors named "T L Gayathri"
Purpose: The study assessed the caries risk in infants and children with and without early childhood caries (ECC) using American Academy of Pediatric Dentistry Caries Risk Assessment Tool (AAPD CRAT) and identified the association between caries risk and mode of birth delivery.
Methods: This cross-sectional study included 96 infants and children with all maxillary and mandibular primary anterior teeth and at least two primary molars erupted clinically in the oral cavity. The details on the mode of birth delivery were noted in a preformed template along with the demographic details, followed by caries risk assessment (CRA) to assess the caries risk of an individual.
Objective: Enamelin is the largest enamel matrix protein encoded by the ENAM gene. The primary purpose of this study was to identify genetic variants in ENAM exon 10 that can alter susceptibility to early childhood caries (ECC).
Methods: This case-control study included 248 children aged 3-6 years, with 124 children diagnosed with ECC in the case group and 124 children without caries in the control group.
AMELX gene association to early childhood caries in south-Indian children: a case-control study.
Eur Arch Paediatr Dent
April 2024
Purpose: Genetic variants of AMELX gene can affect the protein content, organization of enamel prisms, microstructure and microhardness of the enamel, thus altering the caries susceptibility. The present study aims to assess the association between polymorphisms rs17878486, rs5934997, and rs5933871 of AMELX gene and Early Childhood Caries (ECC).
Materials And Methods: This case-control study was conducted on 200 participants, aged 3-6 years, with 100 controls and 100 children with ECC.
Article Synopsis
- Recombinant biopharmaceuticals, such as antibodies and hormones, are produced using plant molecular pharming, which offers benefits like scalability and reduced contamination risks compared to traditional methods.
- Despite its advantages, plant systems face challenges like non-human post-translational modifications and protein instability that hinder efficient protein expression.
- Artificial intelligence and synthetic biology tools are being integrated to improve protein production in plants by optimizing stability and effectiveness, helping meet the growing demand for therapeutics.
The interdigital gland is a specialized skin gland located between the digits of Artiodactyla (i.e., even-toed ungulates).
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