Publications by authors named "T L DELORME"
Circadian (24-h) rhythms in the suprachiasmatic nucleus (SCN) are established in utero in rodents, but rhythmicity of peripheral circadian clocks appears later in postnatal development. Since peripheral oscillators can be influenced by maternal feeding and behavior, we investigated whether exposure to the adverse environmental conditions of limited bedding (LB) during postnatal life would alter rhythmicity in the SCN, adrenal gland and liver in neonatal (postnatal day PND10), juvenile (PND28) and adult rats. We also examined locomotor activity in adults.
View Article and Find Full Text PDFBackground: Intrathecal analgesia plays a key role for patients suffering refractory cancer pain. Nevertheless, intrathecal drug delivery systems (IDDS), requiring a cervical catheter tip implantation, have been poorly described in medical literature.
Aims: A monocentric retrospective follow-up study was designed to evaluate results of cervical IDDS for cancer pain.
Article Synopsis
- - The study examines the risk of bowel obstruction after incisional hernia repair (IHR) using intraperitoneal mesh (IPOM), which is the current standard treatment that can enhance quality of life but poses some risks.
- - Researchers compared a group of 815 patients who underwent laparoscopic IHR with IPOM to a control group of 1630 patients with similar surgical histories without IHR, tracking bowel obstruction incidents over five years.
- - Findings indicate that the IPOM group had a significantly higher rate of bowel obstruction (7.36%) compared to the control group (4.42%), suggesting that laparoscopic IPOM increases the risk of bowel obstruction post-surgery.
Most individuals with neurodevelopmental disorders (NDDs), including schizophrenia and autism spectrum disorders, experience disruptions in sleep and circadian rhythms. Epidemiological studies indicate that exposure to prenatal infection increases the risk of developing NDDs. We studied how environmental circadian disruption contributes to NDDs using maternal immune activation (MIA) in mice, which models prenatal infection.
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