Publications by authors named "T Kusano"
A 3-dimensional (3D) cell culture is now being actively pursued to accomplish the in vivo-like cellular morphology and biological functions in cell culture. We recently obtained nano-fibrillated bacterial cellulose (NFBC). In this study, we developed a novel NFBC-based 3D cell-culture system, the OnGel method, and the Suspension method.
View Article and Find Full Text PDFThe brain is an organ that consumes a substantial amount of oxygen, and a reduction in oxygen concentration can rapidly lead to significant and irreversible brain injury. The progression of brain injury during hypoxia involves the depletion of intracellular adenosine triphosphate (ATP) due to decreased oxidative phosphorylation in the inner mitochondrial membrane. Allopurinol is a purine analog inhibitor of xanthine oxidoreductase that protects against hypoxic/ischemic brain injury; however, its underlying mechanism of action remains unclear.
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- Polymerase chain reaction-based open reading frame typing (POT) was used to study MRSA strains from neonatal intensive care units, focusing on their relationship with nosocomial infections and specific genes.
- In total, 44 MRSA strains were analyzed, revealing 14 different POT types, with 28 strains identified as nosocomial infections and 11 strains carrying toxin-producing genes.
- The study concluded that while certain POT types are associated with nosocomial infections, there wasn't a clear link between the presence of toxin-producing genes or antiseptic resistance and these infections, suggesting other factors may play a role.
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- Resistance exercise impacts gene expression in skeletal muscle by both increasing and decreasing various genes, but detailed studies on how these changes occur over time have been limited.
- In this study, researchers used electrical stimulation to induce muscle contractions in rats and analyzed the changes in muscle transcriptome at different time points after exercise to understand mRNA dynamics.
- The results showed that genes involved in muscle growth and mechanical response displayed varying patterns of upregulation, and the level of mRNA expression was positively linked to protein synthesis 12 hours post-exercise, highlighting the importance of mRNA dynamics in muscle adaptation.
Introduction: Robotic-assisted surgery has become increasingly popular because of its potential benefits. Anatomical liver resection (ALR) is a valuable strategy in hepatocellular carcinoma (HCC) management. ALR with indocyanine green (ICG) fluorescence navigation was reported as an effective solution for segment identification.
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