CORRELATION OF THYROID AUTOIMMUNITY WITH ATHEROSCLEROSIS EVALUATION IN HASHIMOTO'S THYROIDITIS.

The relationship between subclinical hypothyroidism (SH) and Atherosclerotic (At) cardiovascular diseases (CVD) has been one of the most popular topics but causal connection between Hashimoto thyroiditis (HT), lipid profile and follicular epithelial molecular biology is controversial. We investigated 3 groups of patients (group I - HT, group II - HT+At, group III - At). All laboratory tests for thyroid function and lipid profile detection were used according to international guideline recommendations, coronary and femoral arteries intima-media thickness (IMT) were tested by high-resolution ultrasonography, thyroid gland histology and immunohistochemistry carried out by p63 and S100 protein expression control.

Science and conscience.

Many historical facts, describing exploitation and discrimination of research subjects which have been justified by the importance of research aims, are known. Today the protection of the rights and safety of persons involved in biomedical research (research subjects) is the necessary precondition for contemporary biomedical researches and correspondingly, development of the science. An integral responsibility of researchers working in the field of biomedicine is to ensure the protection of safety and rights of research subjects.