Impact of inpatient management of hyperglycemia on peripheral T cell markers in patients with type 2 diabetes.

Unlabelled: Immune cell function is impaired in hyperglycemic patients with diabetes but thought to improve with normalization of blood glucose levels. In this study, we hypothesized that this improvement might involve changes in T cell function. We compared the peripheral T cell markers between the people with and without type 2 diabetes (T2D) admitted to our hospital for glycemic control, and then in patients with T2D before and after the improvement of hyperglycemia by inpatient treatment.

Clinical and radiographic results after ACL reconstruction using an adjustable-loop device.

Background: The femoral cortical suspension device such as fixed loop devices (FLD) and adjustable-loop device (ALD) are used for ACLR technique in recent days. However, there was few studies of clinical and radiographic results for ACLR using ALD. This study was conducted to clarify the clinical and radiographic results, stability and bone tunnel enlargement after ACLR using a ToggleLoc with a zip loop as ALD.

Improved Osseointegration of a TiNbSn Alloy with a Low Young's Modulus Treated with Anodic Oxidation.

Ti6Al4V alloy orthopedic implants are widely used as Ti6Al4V alloy is a biocompatible material and resistant to corrosion. However, Ti6Al4V alloy has higher Young's modulus compared with human bone. The difference of elastic modulus between bone and titanium alloy may evoke clinical problems because of stress shielding.

Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir-induced Fanconi syndrome: a case report.

Background: Adefovir dipivoxil is a nucleotide analogue that is approved for treatment of chronic hepatitis B. Adefovir dipivoxil is associated with proximal tubular dysfunction, resulting in Fanconi syndrome, which can cause secondary hypophosphatemic osteomalacia. We describe a case of a patient with hypophosphatemic osteomalacia secondary to Fanconi syndrome induced by adefovir dipivoxil concomitantly with osteoporosis in whom clinical symptoms were improved by adding denosumab (a human monoclonal antibody targeting the receptor activator of nuclear factor-κB ligand) to preceding administration of vitamin D.

A potential function-based scalpel navigation method that avoids blood vessel groups during excision of cancerous tissue.

This study developed support software for liver surgeons; the software can apply potential functions to blood vessels and cancerous tissue and can adjust repulsion and attraction accordingly. Thus, the scalpel can be directly provided with the power to operate on cancerous cells only from a fixed distance, and accidental cutting of blood vessels can be avoided. The direct support provided by this force navigation allows physicians to safely and reliably navigate past blood vessel groups in order to precisely perform excision surgery for liver cancer.