Early stage epithelial ovarian cancers: a study of morphologic prognostic factors.

We intended to reevaluate the morphologic prognostic factors for early-stage ovarian carcinomas. We reviewed 111 patients diagnosed with early-stage ovarian cancer who had undergone primary surgery at Hacettepe Hospital between 1984 and 2001, using diagnostic criteria from the WHO-2003 classification. We applied the Universal grading system suggested by Shimizu/Silverberg and noted FIGO-stage, histotype, tumor size, bilaterality, and endometriosis.

Human papillomavirus types in invasive cervical cancer specimens from Turkey.

The main aim of the study is to describe the human papillomavirus (HPV) type-specific distribution in invasive cervical cancer (ICC) specimens from Turkey. Paraffin-embedded ICC specimens were identified from the histopathologic archives of the Hacettepe University Medical School in Turkey. HPV detection was carried out through amplification of HPV DNA by a SPF-10 broad-spectrum primer polymerase chain reaction and subsequently followed by DNA enzyme immunoassay and genotyping by LiPA25 (version 1).

Light and electron microscopic evaluation of cardinal ligaments in women with or without uterine prolapse.

Introduction And Hypothesis: This study investigated light and electron microscopic findings in cardinal ligaments of women with or without uterine prolapse.

Methods: Cardinal ligament samples were obtained from hysterectomy specimens of ten women with and ten women without uterine prolapse.

Results: Light microscopy showed altered connective tissue properties in eight of ten women with prolapse and in only three of ten women without prolapse (p = 0.

Four synchronous female genital malignancies: the ovary, cervix, endometrium and fallopian tube.

Objective: To present a unique case of a 63 year-old woman with coexistent adenocarcinoma of the ovary, endometrium, cervix and fallopian tube.

Materials And Methods: A case report from a tertiary health center.

Results: A woman presenting with postmenopausal bleeding and abdominal distantion was assessed by endometrial biopsy and explorative surgery.

Xanthogranulomatous endometritis: a challenging imitator of endometrial carcinoma.

Xanthogranulomatous inflammation is a distinguished histopathological entity affecting several organs, predominantly the kidney and gallbladder. So far, only a small number of cases of xanthogranulomatous inflammation occurring in female genital tract have been described, most frequently affecting the endometrium and histologically characterized by replacement of endometrium by xanthogranulomatous inflammation composed of abundant foamy histiocytes, siderophages, giant cells, fibrosis, calcification and accompanying polymorphonuclear leucocytes, plasma cells and lymphocytes of polyclonal origin. We present a case of a 69-year-old female complained of post menopausal bleeding and weight loss.