Publications by authors named "T Kreusch"
Objective: Tympanic membrane (TM) thickness is an important parameter for differentiation between a healthy and a pathologic TM. Furthermore, it is needed for modeling the middle ear function. Endoscopic optical coherence tomography (eOCT) provides the opportunity to measure the TM thickness of the entire TM in vivo.
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- Genome-wide association studies (GWAS) have provided significant insights into the genetic causes of orofacial clefting (OFC), but challenges arise due to the moderate effect sizes of noncoding risk variants and difficulty in accessing relevant tissues.
- An alternative method to understand the genetic mechanisms is to identify rare variants with stronger effects by focusing on specific mutations and analyzing genomic regions associated with OFC.
- The study reports a targeted resequencing approach using a multiethnic population to identify likely harmful rare variants in candidate regulatory regions linked to nonsyndromic cleft lip/palate, offering a scalable framework for exploring other congenital conditions.
This report focuses a defect comprising the complete mandible due to osteonecrosis, including both condyles, that required bilateral temporomandibular joint (TMJ) reconstruction with complete mandibular corpus using a computer-aided-design and computer-aided-manufacturing(CAD-CAM) planning to harvest a scapula chimeric free flap combined with plate including bilateral alloplastic TMJ prosthesis. This procedure was realized in one and the same surgery. A 73 year-old-man developed an osteoradionecrosis of the total mandible including both condyles after radiation therapy for a squamous cell carcinoma of the tongue base(cT4aN2bM0G3).
View Article and Find Full Text PDFKenny-Caffey syndrome (KCS) is a rare genetic condition characterized by growth retardation, bone abnormalities, and hypoparathyroidism. Herein, we report an unusual case of a 10-year-old girl with Kenny-Caffey syndrome type 2 (KCS2) presenting with vision impairment-suspected maculopathy and intellectual disability. Endocrine evaluation showed low calcium and high phosphorus plasma levels.
View Article and Find Full Text PDFObjectives: There are few data available regarding the clinical course of tick-borne encephalitis virus (TBEV) vaccination breakthrough infections. The published studies suggest that vaccination breakthrough infections may have a more severe course than native TBEV infection in unvaccinated individuals-potentially due to antibody-dependent enhancement. Here we report a large analysis of vaccination breakthrough infections.
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