Publications by authors named "T Kocjan"
Article Synopsis
- Pituitary adenomas are benign tumors that make up about 18% of intracranial tumors and often require surgery, where distinguishing between healthy pituitary tissue and adenoma is critical to avoid complications.
- A study involving 34 patients with non-functional macroadenomas tested the effectiveness of ICG dye during surgery, comparing outcomes with a control group; hormone functions were assessed pre and postoperatively.
- Results showed that postoperative diabetes insipidus occurred in 5.9% of the ICG group versus 23.5% in the control group, but overall adenohypophysis function worsened in a higher percentage of the ICG group, leading to the conclusion that the dye's benefits remain unproven and
Article Synopsis
- This article discusses the modeling of high-strength steel SZBS800's response to strain rates using a combination of standard tensile tests and a unique method involving shooting a ball into specimens.
- The authors employed the Cowper-Symonds viscoplastic model to factor in strain-rate effects and estimated its parameters through a systematic procedure involving rough estimates and fine-tuning techniques.
- Optimal parameter values were determined using explicit dynamic simulations and a genetic algorithm, effectively capturing the material's response, although the optimal candidates spanned a wide range for some parameters.
Background: Clinical practice guidelines recommend the Lateralization Index (LI) as the standard for determining surgical eligibility in primary aldosteronism (PA). Our goal was to identify the optimal LI cut-offs in adrenal venous sampling (AVS) for diagnosing PA that is amenable to surgical cure.
Methods: We conducted a retrospective international cohort study across 16 institutions in 11 countries, including 1,550 patients with PA who underwent AVS, with and/or without ACTH stimulation.
Background: Current guidelines and consensus documents recommend withdrawal of mineralocorticoid receptor antagonists (MRAs) before primary aldosteronism (PA) subtyping by adrenal vein sampling (AVS), but this practice can cause severe hypokalemia and uncontrolled high blood pressure. Our aim was to investigate if unilateral PA can be identified by AVS during MRA treatment.
Methods: We compared the rate of unilateral PA identification between patients with and without MRA treatment in large data sets of patients submitted to AVS while off renin-angiotensin system blockers and β-blockers.
Menopause is a state of estrogen deficiency that affects numerous estrogen-dependent tissues in the female body. Skin is one of the most affected organs. Many consider menopausal skin changes to be merely an aesthetic problem; however, they can significantly affect women's quality of life.
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