Publications by authors named "T Klok"
Successful Introduction of Peanut in Sensitized Infants With Reported Reactions at Home.
J Allergy Clin Immunol Pract
December 2024
Article Synopsis
- Early introduction of peanut for high-risk infants may help prevent peanut allergies, but it's unclear how to best diagnose reactions reported at home.
- In a study of 186 infants who had reactions to peanut, 69% showed sensitization, but 73% of the oral food challenges were negative, allowing safe home introduction of peanut.
- After 6 months, 96% of infants continued consuming peanut regularly without reactions, indicating that testing can prevent misdiagnosis and support long-term tolerance.*
The worldwide rising prevalence of food allergy is a major public health concern. Standard care consists of allergen avoidance and rescue medication upon accidental exposure. Oral immunotherapy (OIT) is increasingly being studied as a treatment option.
View Article and Find Full Text PDFArticle Synopsis
- Early introduction of peanuts can help prevent peanut allergies in infants, but the ideal timing for introduction is still uncertain, especially for those with prior sensitization.
- A study involving infants at pediatric centers in the Netherlands found that a significant portion (23%) were sensitized to peanuts before their first exposure, with certain risk factors like age and eczema severity affecting outcomes.
- The findings recommend introducing peanuts before 8 months of age, particularly in infants with moderate to severe eczema, to minimize the risk of allergic reactions during the first exposure.
Background: Adherence is essential for the long-term efficacy of allergen immunotherapy (AIT) and has been evaluated in numerous retrospective studies. However, there are no published guidelines for best practice in measuring and reporting adherence or persistence to AIT, which has resulted in substantial heterogeneity among existing studies. The 'adherence and persistence in AIT (APAIT)' checklist has been developed to guide the reporting, design and interpretation of retrospective studies that evaluate adherence or persistence to AIT in clinical practice.
View Article and Find Full Text PDFA good nasal passage is crucial for neonates and infants, as they rely on obligate nasal breathing. Feeding problems and dyspnoea are commonly seen in infants with nasal obstruction.In this article, we emphasize the importance of relieving nasal congestion caused by an infection.
View Article and Find Full Text PDF