Publications by authors named "T Kitabayashi"
Background: Naldemedine is an orally available peripherally acting μ-opioid receptor antagonist approved to treat opioid-induced constipation (OIC). It is contraindicated for patients with known or suspected gastrointestinal obstruction to protect against naldemedine-induced perforation. Here, we report a clinical case of suspected perforation of a diverticulum in the sigmoid colon associated with naldemedine.
View Article and Find Full Text PDF: Nivolumab has been shown to improve the overall survival (OS) of patients with recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC). However, there is a need to identify factors associated with long-term survival (beyond 2 years) in these patients. This study investigated the relationship between pretreatment factors and long-term survival in patients with R/M HNSCC treated with nivolumab.
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- - Posterior cerebral artery (PCA) aneurysms are rare and challenging to treat, often requiring surgical methods like neck clipping and trapping; the authors report on a case where they treated a partially thrombosed PCA aneurysm using a combination of trapping and endovascular coil embolization.
- - A 21-year-old woman experienced sudden headaches due to a partially thrombosed aneurysm in her left PCA, which led to surgery after previously improving but then reoccurring headaches caused by aneurysm enlargement.
- - The surgery involved embolizing the aneurysm to stop blood flow before trapping, and ultimately, aneurysm excision was performed to prevent regrowth, resulting in an uneventful postoperative recovery and no recurrence after 2 years
Background: There is a need to develop biomarkers for a more efficient use of immune checkpoint inhibitors (ICIs). Recently, it has been reported that peripheral blood components, including eosinophils, may be effective ICI biomarkers. This study was designed to evaluate the prognostic value of eosinophils for measuring the effects of nivolumab on recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC).
View Article and Find Full Text PDFOrganic light-emitting diodes (OLEDs) have been widely used, particularly in display applications. OLEDs are easily degraded without stringent encapsulation owing to their susceptibility to water vapor and oxygen. Therefore, establishing an effective protection method for these devices is essential.
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