Publications by authors named "T Kiderlen"

Article Synopsis
  • Oncological patients experience higher risks of infections due to weakened immune systems from diseases or treatments, yet vaccination rates against respiratory pathogens like Streptococcus pneumoniae and influenza are low.
  • In a study analyzing 370 oncology patients, only 28.1% were vaccinated against influenza and 32.2% against Streptococcus pneumoniae, with just 7.3% meeting German vaccination recommendations.
  • The findings highlight a significant gap in vaccination coverage, particularly among patients with thoracic cancers, indicating the need for improved vaccination strategies for this high-risk group.
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Aim: Monitoring electronic patient-reported outcomes (ePRO) can provide various benefits to cancer patients, such as enhanced quality of life, reduction of hospital admissions, and even prolonged survival. Furthermore, ePRO might offer significant benefits to patients under antineoplastic treatment in the context of the current COVID-19 pandemic. However, evidence on feasibility of ePRO in routine cancer care and barriers met in a real-life setting remains limited.

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Objective: By implementing a focused must-have vaccination strategy (Easy Vaccination in Oncology [EVO]), we aimed to increase rates for high-impact vaccinations (Streptococcus pneumoniae, influenza, herpes zoster and hepatitis B) in the at-risk population of oncological patients.

Methods: In this German multicentre interventional non-randomised controlled two-arm open trial with repeated cross-sectional data collection, we evaluated the EVO strategy as an easy to implement approach. Vaccination rates were assessed in the outpatient setting and re-assessed after 3 months.

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Treatment of metastasized malignant melanoma still has very limited therapeutic options. After exhaustion of immuno-checkpoint inhibition (ICI) and potentially targeted therapy, no promising alternatives are currently available. We report on an 83-year-old patient suffering from disseminated metastatic melanoma who showed an almost complete response to ICI following chemotherapy, after repeated failure of different regimens including two nonresponsive regimens of ICI.

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