Publications by authors named "T Khawaja"
Background: Early in the COVID-19 pandemic, convalescent plasma (CP) emerged as a potentially effective treatment neutralising SARS-CoV-2. Early CP therapy with high neutralising antibody (NAb) titre may benefit COVID-19 outpatients and, in sufficient quantities even some hospitalised patients. This study details the process of setting up a CP bank, containing high- and low-titre CP for a clinical trial.
View Article and Find Full Text PDFPurpose Of Review: Body fat distribution plays a significant role in the cardiometabolic consequences of obesity. We review the impact of visceral and hepatic fat and highlight important interventions.
Recent Findings: Several epidemiologic studies have established a clear association between visceral fat and cardiovascular disease.
Article Synopsis
- Multi-drug resistant (MDR) E. coli is a significant public health issue, especially in developing regions like the global south, with travelers spreading it to other areas.
- A study in Punjab, Pakistan, involved 494 outpatients and 423 community members, analyzing the genetic diversity of E. coli and its antimicrobial resistance (AMR) by collecting and sequencing stool samples, resulting in 5,247 genomes from 1,411 samples.
- The research found that the genetic lineages and AMR profiles of E. coli in the Punjabi population differed notably from those in high-income countries, and antibiotic use was linked to increased prevalence of MDR strains, highlighting the need for ongoing regional genomic surveillance to understand and manage this
Introduction: Convalescent plasma (CP) emerged as potential treatment for COVID-19 early in the pandemic. While efficacy in hospitalised patients has been lacklustre, CP may be beneficial at the first stages of disease. Despite multiple new variants emerging, no trials have involved analyses on variant-specific antibody titres of CP.
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