[EXPERIMENTAL MODELS OF STRESS URINARY INCONTINENCE].

Despite numerous medical and surgical treatment strategies available, the problem of stress urinary incontinence (SUI) in women is still not completely resolved. Continuing research is underway to modify the sling operations and develop new bulk-enhancing agents, including the use of tissue engineering and cell technologies. To evaluate the safety and effectiveness of new methods at the preclinical stage, adequate and reproducible experimental models of SUI in laboratory animals should be used.

Compression asymmetric static experimental model of degenerative disk diseases.

We propose an experimental model of degenerative-dystrophic changes in intervertebral disks of rat tail. The results of X-ray examination and histological studies showed that degenerative changes in the disk tissues caused by experimental compression of intervertebral disks in rat tails are identical to those in humans.