Publications by authors named "T Kashiwadate"
Introduction: Mutated human epidermal growth factor receptor 2 (HER2) is an oncogene with critical pathogenic roles in breast cancer. HER2-low-positive breast cancer is a recently described subtype. We aimed to explore the clinical and molecular characteristics of gastric cancer with low HER2 expression, drawing on recent developments in breast cancer subtypes.
View Article and Find Full Text PDFThe current study aimed to identify the indications for manual reduction in incarcerated obturator hernias (OH). Further, whether time to symptom onset and manual reduction outcomes can be predictors of bowel viability and the need for bowel resection in incarcerated OH were examined. This retrospective study included 26 patients with incarcerated OH who underwent surgery.
View Article and Find Full Text PDFErythropoietic protoporphyria (EPP) is a very rare disease with an estimated prevalence of 1 in 200,000 individuals. Decreased ferrochelatase activity causes the accumulation of protoporphyrin in the body, and light exposure results in the generation of active oxygen, causing photosensitivity. Liver damage has the greatest influence on the prognosis, and liver transplantation is the only treatment option for patients with decompensated liver cirrhosis.
View Article and Find Full Text PDFArticle Synopsis
- This study examined the potential of the biomarker M2BPGi for assessing liver fibrosis in pediatric patients who have undergone liver transplantation, addressing a need for noninvasive markers.
- Researchers analyzed data from 96 pediatric liver transplant patients and found that M2BPGi levels showed some correlation with other fibrosis markers but did not significantly predict liver graft fibrosis.
- The findings suggest that M2BPGi has limitations as an assessment tool for liver graft fibrosis, highlighting the need for further research with larger patient groups.
Article Synopsis
- - The text discusses a clinical trial on machine perfusion for kidney transplants in Japan, aiming to boost the use of this technique due to its potential benefits for organ preservation.
- - Thirteen kidney transplant procedures were performed using a specific machine that maintains optimal conditions for the organs, with details on donor types and recipient demographics highlighted.
- - The results indicated successful preservation with no primary non-functional cases, showing promise for machine perfusion as a method for using marginal donor organs in Japan.