Pharmacokinetics of multiple-dose administered gentamicin to unilaterally nephrectomized rabbits.

The aim of this study was to investigate the effect of unilateral nephrectomy on the pharmacokinetics of gentamicin. The study was carried out on 19 male rabbits. Gentamicin was injected i.

Effect of unilateral nephrectomy in rabbits on pharmacokinetics of salicylate.

The pharmacokinetics of salicylate was investigated in rabbits 6 months after unilateral nephrectomy. Sodium salicylate was given through the stomach gauge once in a dose of 20 mg/kg. Pharmacokinetic calculations assuming one compartment open model have revealed that in nephrectomized rabbits area under the curve (AUC) was increased by 131%, t0.

Effect of unilateral nephrectomy on the pharmacokinetics of rolitetracycline in rabbits.

An analysis of the single-dose pharmacokinetics of rolitetracycline in rabbits after unilateral nephrectomy is presented. Rolitetracycline was injected i.v.