Publications by authors named "T Kanie"
Article Synopsis
- ST-segment elevation myocardial infarction complicated by cardiogenic shock (STEMI-CS) has high mortality rates, especially for patients admitted during off-hours, known as the "off-hours effect."
- This study analyzed registry data of 1,207 patients treated with Impella, revealing that 42.1% of off-hours admissions resulted in death compared to 30.3% during on-hours.
- The research concluded that off-hours admissions were linked to a 60% increased risk of 30-day mortality, emphasizing the need for improved cardiovascular care and timely treatment during off-hours.
Severe aortic valve stenosis (AS) often coexists with mitral valve stenosis (MS). MS aggravation after transcatheter aortic valve replacement (TAVR) is common, and its etiology is multifactorial. We hypothesized that geometric changes in the mitral complex (mitral valvular and annular deformities) are adjunctive factors aggravating MS after TAVR, particularly in older adults with a smaller left ventricle (LV).
View Article and Find Full Text PDFBackground: Vessel-level physiological data derived from pressure wire measurements are one of the important determinant factors in the optimal revascularisation strategy for patients with multivessel disease (MVD). However, these may result in complications and a prolonged procedure time.
Aims: The feasibility of using the quantitative flow ratio (QFR), an angiography-derived fractional flow reserve (FFR), in Heart Team discussions to determine the optimal revascularisation strategy for patients with MVD was investigated.
Background: Tetraspanin CD151 is highly expressed in endothelia and reinforces cell adhesion, but its role in vascular inflammation remains largely unknown.
Methods: In vitro molecular and cellular biological analyses on genetically modified endothelial cells, in vivo vascular biological analyses on genetically engineered mouse models, and in silico systems biology and bioinformatics analyses on CD151-related events.
Results: Endothelial ablation of leads to pulmonary and cardiac inflammation, severe sepsis, and perilous COVID-19, and endothelial CD151 becomes downregulated in inflammation.
Objective: To explore the taxonomic and predicted functional relationship between the urine microbiome and alterations of semen analysis (SA) parameters.
Design: Cross-sectional study.
Setting: Academic medical center.