Publications by authors named "T Kandashvili"

Patients with myocardial infarction (MI) have both major depression as well as depressive symptoms. Therefore, due to the high prevalence of depression in post-MI patients, an assessment of its prognostic importance was put on the agenda. Patients after ACS frequently report fatigue, sleep problems, and sadness.

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Accumulating evidence showed that chronic inflammation is a risk factor for increased cardiovascular mortality in the population with Kidney Failure (KF) remaining on Kidney Replacement Therapy (KRT). The gut microbiome is altered in patients with Chronic Kidney Disease (CKD) and is one of the major sources of chronic inflammation. Uremic gut microbiome may have serious effects on patients' quality of life (QoL) and, especially, on their psychological, social, and economic prosperity.

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Ventral hernias, with the incidence of reherniation nearly as high as 50%, still remain to be a real challenge for surgeons worldwide. The use of mesh in the repair of abdominal wall defects reduces the incidence of reherniation; however, using a prosthetic mesh can lead to complications like wound infection, hematoma, seroma, enterocutaneous fistula, small bowel obstruction, recurrent herniation and erosion into adjacent structures including the intestine. The aim of the study was to develop a method for producing gelatin-coated decellularized and lyophilized human amniotic membrane graft and to determine its effectiveness for the reconstruction of the anterior abdominal wall defects.

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Using the mesh for hernia repair is the most common type of hernia surgery. There are many types of meshes made of various synthetic materials, but all of these meshes have their own respective disadvantages. The aim of this study was to provide preliminary results of a non-randomized clinical trial evaluation of novel porcine grafts XI-S+® (Colorado Therapeutics LLC.

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To evaluate effects of potentially hepatotoxic factors on the body we have studied medical histories of 3382 patients hospitalized at the toxicoresuscitation unit of the TSU Clinical Hospital and at the University Therapy Clinic of the City Hospital N1 during 2000-2004. It was found out that the most common etiologic causes of intoxication are medicines and alcohol. The role of chemical substances is also significant.

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