Publications by authors named "T Kahraman"
Objectives: To investigate the effect of telerehabilitation-based graded motor imagery (MI, GMI) training on pain and pain-related factors in people with multiple sclerosis (MS).
Design: Randomized controlled, assessor-blind pilot trial with repeated-measure design.
Setting: Neurology outpatient clinic.
Extracellular vesicles (EVs), secreted by almost all living cells, have gained significant attention for their role in intercellular communication and their potential as versatile carriers for biotherapeutics. However, the clinical translation of EV-based therapies faces significant challenges, primarily due to the lack of efficient methods for loading biotherapeutic agents into EVs. This study introduces a simple, reproducible strategy for the simultaneous incorporation of various biotherapeutics within EVs.
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- The study aimed to evaluate the reliability and validity of three questionnaires designed to assess dual-tasking difficulties in people with multiple sclerosis (PwMS).
- A total of 356 participants across six countries were analyzed, showing that the questionnaires had strong test-retest reliability and internal consistency, with the DIDA-Q performing the best.
- The findings indicate that these self-reported questionnaires are effective tools for measuring the impact of dual-task challenges on the daily lives of ambulatory PwMS in both research and clinical settings.
Background: The timed walk test is essential for assessing the functional capacity of persons with multiple sclerosis (MS). When a decline in ambulation ability and loss of function in the later stages of MS is observed, it is imperative to utilize alternative methods for measuring functional capacity.
Objective: To investigate the validity and reliability of the Six-Minute Pegboard Ring Test (6PBRT) in persons with MS.
Background: The COVID-19 pandemic has caused significant morbidity and mortality globally. The role of plasma-derived extracellular vesicles (EVs) in pediatric COVID-19 patients remains unclear.
Methods: We isolated EVs from healthy controls (n = 13) and pediatric COVID-19 patients (n = 104) with varying severity during acute and convalescent phases using serial ultracentrifugation.