Publications by authors named "T Kadosaka"
Normalization of increasing shocking coil impedance with full output synchronized shock.
J Cardiovasc Electrophysiol
November 2024
Article Synopsis
- - Impedance is an important factor for cardiovascular implantable electronic devices (CIEDs), and low voltage sub-threshold measurement (LVSM) is commonly used to measure it, although it can sometimes be inaccurate due to tissue changes.
- - A case study showed that elevated LVSM shock impedance (LVSM-SI) occurred 8 years after lead implantation, likely due to tissue encapsulation around the lead, but normal values were found after administering a high voltage shock.
- - The study suggests that performing a full-output synchronized shock test can help evaluate high voltage shock impedance (HVSI) when LVSM-SI readings are abnormal, potentially restoring normal LVSM-SI values.
Article Synopsis
- Epicardial adipose tissue (EAT) influences atrial fibrillation (AF) but its role in postoperative AF (POAF) is not well understood; this study examines how EAT relates to POAF in cardiovascular surgery patients.
- Out of 53 patients, 34% experienced POAF within a week after surgery, but no major differences in EAT profiles were found between patients with and without POAF.
- Key findings include that higher levels of tumor necrosis factor-alpha (TNF-α) mRNA are linked to increased POAF risk, while larger adipocyte sizes correlate inversely with POAF onset; mitochondrial OXPHOS was unrelated to POAF but associated with secretory activities and adipocyte
Article Synopsis
- Scientists are studying a new way to treat a heart problem called atrial fibrillation (AF) using special light instead of painful electric shocks.
- This method uses light to change how cells in the heart behave, which could potentially stop the heart from beating too fast.
- The study found that shining light on the heart cells helped them stay in a normal rhythm, showing that this technique might be a promising and painless treatment for heart issues in the future.
Article Synopsis
- Recent studies indicate that SGLT2 inhibitors like empagliflozin may lower the risk of atrial fibrillation in diabetes patients by reducing oxidative stress linked to mitochondrial-ROS generation.
- In a rat model of type-2 diabetes, treating with empagliflozin improved heart function by reducing atrial tachyarrhythmia, fibrosis, and mitochondrial dysfunction that are exacerbated in diabetes.
- The findings highlight empagliflozin's potential to enhance mitochondrial health and cardiac function, suggesting it could serve as a beneficial treatment for diabetes-related heart issues.
Fragmented QRS (fQRS) on a 12-lead electrocardiogram is a known marker of fatal arrhythmias or cardiac adverse events in ischemic and non-ischemic cardiomyopathy patients. Nonetheless, the association between fQRS and clinical outcomes in patients with cardiac sarcoidosis (CS) remains unclear. Herein, we investigated whether fQRS is associated with long-term clinical outcomes in CS patients.
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