Publications by authors named "T K Timmers"

Article Synopsis
  • - The study evaluated the use of computer-assisted history taking (CAHT) systems to collect orthopedic patients' medical histories before their first outpatient consultations to improve efficiency and patient engagement.
  • - A multicenter implementation study saw a 92.7% completion rate for the CAHT questionnaires, with patients rating the ease of use and satisfaction with their consultations at 8.0 out of 10.
  • - Physicians recognized significant benefits from the use of CAHT, scoring its added value at 7.8, citing improved efficiency and enhanced medical record completeness when patient responses were utilized during consultations.
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Article Synopsis
  • A study evaluated a personalized eHealth app designed for abdominal aortic aneurysm (AAA) patients undergoing surgery to assess patient satisfaction and feasibility.
  • Out of 65 patients, 91% installed the app, with high satisfaction scores for guidance, information, and overall usefulness, although 10% deactivated it.
  • The app is considered a valuable tool for enhancing prehabilitation and contributes to the digital transformation in healthcare, with users reporting positive lifestyle changes and areas for improvement.
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Telemedicine offers a promising solution to enhance the delivery and personalization of headache care. Integrating electronic (e-)tools enables the objective monitoring of migraine. This study aims to demonstrate the relevance of e-tools for personalized headache care, assess patient and caregiver compliance and satisfaction, and present their use in enhancing care.

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A receptor protein variant lacking 2′,3′-cAMP/cGMP synthetase activity but retaining NADase activity does not induce cell death but confers resistance to Potato virus X.

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The plant homolog of vertebrate necroptosis inducer mixed-lineage kinase domain-like (MLKL) contributes to downstream steps in Toll-interleukin-1 receptor domain NLR (TNL)-receptor-triggered immunity. Here, we show that Arabidopsis MLKL1 (AtMLKL1) clusters into puncta at the plasma membrane upon TNL activation and that this sub-cellular reorganization is dependent on the TNL signal transducer, EDS1. We find that AtMLKLs confer TNL-triggered immunity in parallel with RPW8-type HeLo-domain-containing NLRs (RNLs) and that the AtMLKL N-terminal HeLo domain is indispensable for both immunity and clustering.

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