Front Cell Neurosci
July 2023
The long history of studying the propagation of an action potential has revealed that an electrical signal is accompanied by mechanical and thermal effects. All these effects together generate an ensemble of waves. The consistent models of such a complex phenomenon can be derived by using properly the fundamental physical principles.
View Article and Find Full Text PDFThe propagation of an action potential in nerves is accompanied by mechanical and thermal effects. Several mathematical models explain the deformation of the unmyelinated axon wall (a mechanical wave). In this paper, the deformation of the myelinated axon wall is studied.
View Article and Find Full Text PDFBiomech Model Mechanobiol
December 2020
The in silico simulations are widely used in contemporary systems biology including the analysis of nerve pulse propagation. As known from numerous experiments, the propagation of an action potential is accompanied by mechanical and thermal effects. This calls for an analysis at the interface of physics, physiology and mathematics.
View Article and Find Full Text PDF