Publications by authors named "T K Oates"

Article Synopsis
  • After a tissue injury, inflammatory cells immediately respond to clear debris and manage other cells for repair, but their role can be both beneficial and detrimental.
  • This study examines the use of protocells loaded with R848 to reprogram innate immune cells in zebrafish, observing significant changes in inflammatory responses during skin and skeletal repair.
  • The research shows that R848-reprogrammed macrophages enhance healing outcomes by improving bactericidal activities and positively influencing processes vital for recovery, with findings also applicable to human macrophages.
View Article and Find Full Text PDF
Article Synopsis
  • Developed a new bioactive sealant with calcium fluoride nanoparticles and antibacterial properties to improve fluoride release and sealing ability.
  • The new sealant released significantly more fluoride initially compared to a commercial product and maintained its release after multiple cycles.
  • It showed superior mechanical properties and biocompatibility, indicating potential for effective long-term caries prevention.
View Article and Find Full Text PDF

Objective: The article reviewed novel orthodontic devices and materials with bioactive capacities in recent years and elaborated on their properties, aiming to provide guidance and reference for future scientific research and clinical applications.

Data, Sources And Study Selection: Researches on remineralization, protein repellent, antimicrobial activity and multifunctional novel bioactive orthodontic devices and materials were included. The search of articles was carried out in Web of Science, PubMed, Medline and Scopus.

View Article and Find Full Text PDF

The repair and regeneration of critical-sized bone defects remain an urgent challenge. Bone tissue engineering represents an exciting solution for regeneration of large bone defects. Recently, the importance of innervation in tissue-engineered bone regeneration has been increasingly recognized.

View Article and Find Full Text PDF