Publications by authors named "T K Isaac"

Background Chronic kidney disease (CKD) is prevalent in India, particularly among underprivileged populations. Government initiatives such as the Dr. YSR Aarogyasri Health Insurance Scheme aim to provide affordable healthcare to economically impoverished individuals with kidney diseases.

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This case report describes a patient who presented with devastating stroke-like symptoms secondary to a cystic brain lesion that was confirmed to be glioblastoma without significant symptomatology before her dramatic presentation. It further highlights the aggressive nature and the swift growth of the tumor in a short period of time. A 55-year-old female with no significant past medical history presented to the emergency department in a comatose state.

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Article Synopsis
  • This case report discusses an unusual side effect—anemia—related to clozapine, an atypical antipsychotic used for treatment-resistant schizophrenia.
  • A 70-year-old male patient experienced declining hemoglobin levels during clozapine treatment, despite regular blood monitoring that typically focuses on neutrophil counts.
  • The anemia was likely due to clozapine, with suggestions of potential bone marrow toxicity, highlighting the need for comprehensive blood work to monitor all blood parameters in patients taking this medication.
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Background: Preterm birth and social deprivation are known risk factors for learning difficulties. However there has been little work looking into the interaction between these two risks. We aimed to identify if children born preterm to families with higher levels of social deprivation are disproportionately more likely to have learning difficulties than those with lower levels of social deprivation.

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Objective: We examined what matters to families about the healthcare provided to preterm or LBW infants in hospital and the community, to ensure that care meets the needs of infants and parents.

Methods: We searched databases to identify eligible studies examining the views and expectations of families. Study quality was assessed using the CASP checklist for qualitative studies.

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