Near-infrared germanium PIN-photodiodes with >1A/W responsivity.

Even though efficient near-infrared (NIR) detection is critical for numerous applications, state-of-the-art NIR detectors either suffer from limited capability of detecting incoming photons, i.e., have poor spectral responsivity, or are made of expensive group III-V non-CMOS compatible materials.

Factors Associated with Information Needs and Information-Seeking Intention Among People with Cancer Experience in Hong Kong.

Information is crucial for person-centered cancer care. This study investigated sociodemographic, psychological, and communicative factors associated with perceived information needs and the intention to continue seeking information among individuals with cancer experience in Hong Kong. Data were drawn from the INSIGHTS-Hong Kong (International Studies to Investigate Global Health Information Trends) survey, which included 510 respondents with personal cancer experience or as family members and close friends of those diagnosed with cancer.

Transcriptomic Profiling Reveals Differences in Slow-Twitch and Fast-Twitch Muscles of a Cigarette Smoke-Exposed Rat Model.

Background: Cigarette smoking is known to affect muscle function and exercise capacity, including muscle fatigue resistance. Most studies showed diminished cross-sectional area and fibre type shifting in slow-twitch muscles such as the soleus, while effects on fast-twitch muscles were seldom reported and the differential responses between muscle types in response to exposure to cigarette smoke (CS) were largely unknown. This study aimed to elucidate the histomorphological, biochemical and transcriptomic changes induced by CS on both slow-twitch and fast-twitch muscles.

Dietary Pattern, Sputum DNA Methylation, and Lung Health: An Epidemiological Study in People Who Ever Smoked.

Background: We previously identified a panel of sputum DNA methylation that predicts lung aging and risk for lung cancer.

Research Question: Can the sputum methylation panel be used as a readout to derive a dietary pattern beneficial for lung health? Is this dietary pattern associated with various subjective and objective lung health phenotypes? Does this relationship vary among people who currently smoke (current smokers) vs previously smoked (former smokers)?

Study Design And Methods: Using the Lovelace Smoker Cohort (LSC), we employed the LASSO (least absolute shrinkage and selection operator) regularized Poisson regression to define a dietary pattern for sputum. Associations of the dietary pattern with objective and subjective lung health measurements were examined using generalized linear and Cox models in the LSC and the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening trial.