Publications by authors named "T K Desai"

Background: Thick fetal corpus callosum (CC) is a rare finding and its significance in isolation is not clear. In this retrospective study, we aim to gain insight into the microarchitecture of CC in a cohort of fetuses with thick and short CC (isolated or associated with mild extra-/intracranial abnormalities) as seen on ultrasound (US), by using prenatal magnetic resonance (MR) diffusion tensor imaging (DTI) with fiber tractography, thereby allowing better characterization for postnatal prognosis.

Methods: Twelve fetuses met the inclusion criteria on US.

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Orthodontic relapse is one of the most prevalent concerns of orthodontic therapy. Relapse results in patients' teeth reverting towards their pretreatment positions, which increases the susceptibility to functional problems, dental disease, and substantially increases the financial burden for retreatment. This phenomenon is thought to be induced by rapid remodeling of the periodontal ligament (PDL) in the early stages and poor bone quality in the later stages.

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Pheochromocytomas are rare tumors arising from the chromaffin cells of the adrenal medulla that result in the secretion of excessive catecholamines. They are an uncommon cause of hypertension in the pediatric population. We present a case of a six-year-old male with hypertension, rapid weight loss, palpitations, excessive sweating, and vomiting.

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Article Synopsis
  • In emergency departments, there's an increasing reliance on ultrasound-guided nerve blocks (USGNBs) as an alternative to opioids for acute pain management, but limited research has been conducted on their effectiveness when performed by emergency medicine practitioners.
  • A study at a tertiary care hospital from January 2022 to December 2023 analyzed 274 nerve blocks, measuring patient pain before and after the procedure and considering factors like block type and complications.
  • Results showed significant pain reduction, averaging a decrease of 2.9 points after 15 minutes and 5.8 after 30 minutes, with common blocks being the femoral nerve and fascia iliaca, while some complications were noted.
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Tight junctions regulate epithelial barrier function and have been shown to be influenced by multiple classes of proteins. Apical integrins have been identified as potential regulators of epithelial barrier function; however, only indirect approaches have been used to measure integrin regulation of the epithelial barrier. Here, we used polymeric nanowires conjugated with anti-integrin β1 antibodies to specifically target apically localized integrins in either their closed or open conformation.

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