[Correction of immune and hematopoietic system disorders in experimental toxic hepatitis with Lacto Flor].

Reduction in cells quantity of thymus, lymphatic nodes, bone marrow and rosette formation cells, decrease in erythrocytes and leucocytes number, suppression of antibody production are seen in experimentally developed acute toxic hepatitis (ATH). Lacto Flor preparation was established to have potential properties to restore different immune and hematological systems disorders observed in mice with ATH.

[Effect of Lacto Flor on immunological and hematopoietic systems in experimental hemolytic anemia].

Negative changes in organs of immune and blood systems have been observed under experimentally produced hemolytic anemia. Total recovery of cellularity in central and peripheric immunity organs and blood profile was found with Lactoflor use.

[The comparative efficacy of splenectomy and antilymphocyte globulin therapy in patients with aplastic anemia].

Analysis of the clinical efficacy and long-term survival of patients with grave and not grave forms of aplastic anemia, subjected to splenectomy or treated with antilymphocytic globulin has shown that in grave aplastic anemia, the clinical efficacy of antilymphocytic globulin is higher than the efficacy of the operative treatment methods. The 30-month survival can be attained in 42% of the patients given globulin and in 28% of the patients after splenectomy. In patients with grave aplastic anemia, it is recommended that the treatment be instituted from the use of antilymphocytic globulin in a dose of 15 mg/kg bw daily for 5 days, provided there are no contraindications.