Prevalence of direct antiglobulin test positive in whole blood donors: Study at a tertiary blood center Northern India.

Background: The direct antiglobulin test (DAT) detects red blood cell (RBC) sensitivity to complement or IgG . The clinical disorders of hemolytic disease of the newborn, hemolytic transfusion reaction, and autoimmune and drug-induced hemolytic anemia are some examples of those that can cause coating of RBCs with antibodies or complement autoimmune hemolytic anemia (AIHA). Rarely, DAT is positive in nonimmune-mediated hemolytic anemias as well.

Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol.

Salmonella enterica serotype Typhimurium (Salmonella) resides and multiplies intracellularly in cholesterol-rich compartments called Salmonella-containing vacuoles (SCVs) with actin-rich tubular extensions known as Salmonella-induced filaments (SIFs). SCV maturation depends on host-derived cholesterol, but the transport mechanism of low-density lipoprotein (LDL)-derived cholesterol to SCVs remains unclear. Here we find that peroxisomes are recruited to SCVs and function as pro-bacterial organelle.

Identification of Ecological Hotspots Using the Eco-track: Case of Keoladeo National Park, Bharatpur, India.

Ecological conservation and sustainable land management are vital endeavors in the face of rising anthropogenic pressures and habitat deterioration. Accurate and effective evaluation techniques are essential for identifying regions that are of ecological relevance and concern. The present research introduces an innovative approach using geospatial tools to detect natural hotspots and deficits within a landscape.

Tracheal bronchogenic cyst: a rare cause of stridor.

A 6-month-old child with stridor from 3 months of age presented with interim worsening following a respiratory infection. Airway evaluation revealed a smooth, polypoidal mass herniating in and out of the airway with each respiratory cycle, from the anterior surface of the upper trachea. Computerized tomography showed a non-enhancing cystic mass in anterior neck protruding into the upper trachea through an anterior tracheal defect.

Association of ABO phenotype, rhesus factor, platelet count and hemoglobin level with oral hygiene status and severity of chronic periodontitis.

Background: The development of periodontal diseases has multifactorial causes including genetic factors. Limited investigations have been conducted to explore the association between ABO blood groups and the development and progression of periodontal diseases.

Aim: To evaluate and assess the association of ABO Phenotype and Rhesus factor with oral hygiene status, severity of chronic periodontitis and blood parameters like hemoglobin level and Platelet count in localized and generalized chronic periodontitis.