Publications by authors named "T Jason Bradford"
Background: Pediatric respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (LRTI) commonly requires hospitalization. The Clinical Progression Scale Pediatrics (CPS-Ped) measures level of respiratory support and degree of hypoxia across a range of disease severity, but it has not been applied in infants hospitalized with severe RSV-LRTI.
Methods: We analyzed data from a prospective surveillance registry of infants hospitalized for RSV-related complications across 39 U.
Importance: Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening complication of COVID-19 infection. Data on midterm outcomes are limited.
Objective: To characterize the frequency and time course of cardiac dysfunction (left ventricular ejection fraction [LVEF] <55%), coronary artery aneurysms (z score ≥2.
Visualization of guanine-rich oligonucleotides that fold into G-quadruplex (G4) helical structures is of great interest in cell biology. There is a large body of evidence that suggests that these noncanonical structures form and play important biological roles. A promising recent development highlighted fluorescence lifetime imaging microscopy (FLIM) as a robust technique for the direct and quantitative imaging of G4s in live cells.
View Article and Find Full Text PDFArticle Synopsis
- The CAMP study is an ongoing research project aiming to assess the mid- and long-term effects of myocarditis and pericarditis following the Pfizer-BioNTech COVID-19 vaccine in patients under 21.
- It involves a cohort of at least 200 vaccinated patients and a comparison group of 100 patients with COVID-19 related myocarditis, collecting data over a 5-year span to track health outcomes and complications.
- As of October 16, 2024, the study has enrolled 273 participants, focusing on heart function, complications, and overall quality of life post-illness.
The early evolution of sex chromosomes has remained obscure for more than a century. The Vandiemenella viatica species group of morabine grasshoppers is highly suited for studying the early stages of sex chromosome divergence and degeneration of the Y chromosome. This stems from the fact that neo-XY sex chromosomes have independently evolved multiple times by X-autosome fusions with different autosomes.
View Article and Find Full Text PDF